体外蜂蜜的抗炎性病毒作用:麦卢卡蜂蜜的有效高活性。
摘要来源:
Arch Med Res。 2014年5月28日。epub 2014年5月28日。pmid: 24880005“> 24880005”> 24880005 Matsunaga, Takahiro Haruyama, Nobuyuki Kobayashi
Article Affiliation:Ken Watanabe
Abstract:BACKGROUND AND AIMS: Influenza viruses are a serious threat to human health and cause thousands of deaths annually.因此,迫切需要开发新型抗激素病毒药物。因此,这项研究的目的是评估来自各种来源的蜂蜜的抗炎性病毒活性。阐明可能的机甲使用了蜂蜜作用,斑块抑制测定法。 Synergistic effects of honey with known anti-influenza virus drugs such as zanamivir or oseltamivir were tested.
RESULTS: Manuka honey efficiently inhibited influenza virus replication (IC50 = 3.6 ± 1.2 mg/mL; CC50 = 82.3 ± 2.2 mg/ml;选择性指数= 22.9),这与其病毒效应有关。 In the presence of 3.13 mg/mL manuka honey, the IC50 of zanamivir or oseltamivir was reduced to nearly 1/1000th of their single use.
CONCLUSIONS: Our results showed that honey, in general, and particularly manuka honey, has potent inhibitory activity against the influenza virus,展示潜在的药物价值。