抗炎性的抗炎性特性，从芙蓉菌丝分离出来。
摘要来源：
j ethnopharmacol。 2023年3月1日; 303：115918。 EPUB 2022 11月24日。PMID： 36436715 Cao，Weihong Liang，Yinhua Yang，Tao Huang，Yun-Sang Tang，Bo Liu，Xin Zhao，Pang-Chui Shaw
文章隶属关系：Mengjie Xiao
摘要：
（Fry），芙蓉叶片的叶子是一种用于治疗咳嗽和呼吸系统疾病的中国药草。 Fry是专利药物Fupo Ganmao颗粒的主要草药成分，用于治疗普通感冒。然而，尚未确定其抗激素的活动组件和机制。
MATERIAL AND METHODS: Bioassay guided isolation was performed to get anti-influenza virus components. Influenza virus infected cells and mouse model were employed for efficacy evaluation.
RESULTS: Using bioassay-guided isolation, the flavonoid tiliroside was obtained, which inhibited four IAV strains in MDCK cells with ECranging from 3.87 to 27.61 μM by抑制病毒核糖核蛋白活性。 Tiliroside also significantly downregulated the expression of cytokines/chemokines in A549 cells, and protected 50% of PR8-infected BALB/c mice from death and at 800 mg/kg/day, improved lung edema conditions.
CONCLUSION: Tiliroside is effective for influenza病毒感染治疗和进一步的药物开发有望。这项研究是第一个证明炸牛liro剂对流感病毒作用。