抗肉食和抗炎作用在果糖喂养的雄性大鼠中。
摘要来源:
j j Basic Clin Phill Physiol Pharthape。 2016年6月1日; 27(4):387-91。 PMID: 27383871” Ahmadvand,Alireza Nakhaie
文章隶属关系:Mohammad Reza Shahraki
摘要:
背景: <> <> <> <> This study has been designed to evaluate the anti-nociceptive and anti-inflammatory effects of chronic administration of Withania somnifera root (WSR) in fructose drinking water rats.
METHODS: An experiment was carried out on 48 Wistar-Albino male rats, weighting200±30 g分为六组(n = 8):对照组(C),对照吗啡(CM),W。Somnifera组(WS),接收WSR(62.5 mg/g饮食),W。SomniferaNaloxone Group(WSN),收到了接收WSR和NALOXONE,Fructose(Fructose)的组,并接收了弗洛克酮(Fructose),并接收了弗里克斯(Fructose)的弗里克斯(Fructose)弗里克斯(Fructose),并接受了弗里克斯(Fructose)的弗里克斯(Fructose)。在试验期间的水和WSR。在静电片内注射福尔马林(50μL,1%)后,诱导双相疼痛反应。使用Dubuisson方法测量疼痛行为。使用ANOVA和Tukey测试通过SPSS软件V. 18分析所获得的数据。表达为平均值±SD。统计差异被认为在p <0.05。
结果: 结果表明,结果表明,胰岛素抵抗指数,血糖,胰岛素,IL-6,TNF-6,TNF-α,以及F组中的急性疼痛均大大增加,但与该参数相比,该参与者与该参数相比有了相比的比较。FWS group were significantly decreased compared with the F group (p<0.001).
CONCLUSIONS: Our findings indicated that chronic oral administration of WSR has analgesic and anti-inflammatory effects in fructose drinking water rats and causes improved insulin resistance索引。