姜黄素对肠道肿瘤的抑制与肠道免疫细胞轮廓的变化有关。
摘要来源:
j surg res。 2000年4月; 89(2):169-75。 pmid: 10729246“> 10729246 Bertagnolli
Article Affiliation:Department of Surgery, The New York Presbyterian Hospital, New York, New York, USA.
Abstract:BACKGROUND: The C57BL/6J-Min/+ (Min/+) mouse bears a germline mutation in Apc and is therefore a model for familial adenomatous息肉病和零星结直肠癌。最小/+肠粘膜表现出明显的自发腺瘤形成的趋势。姜黄素是一种以其抗肿瘤和免疫调节功能在体外闻名的酚类抗氧化剂。姜黄素通过可能是R兴高采烈的免疫调节特性。
材料和方法: 研究肠道免疫力和姜黄素诱导的抗肿瘤反应之间的关系 mice.
RESULTS/CONCLUSION: These results show that mucosal CD4(+) T cells and B cells increase in animals treated with curcumin, suggesting that curcumin modulates lymphocyte-mediated immune functions.