[电针刺激敏化穴位的刺激对腹泻促进性的大鼠肠功能障碍的影响。 2017年10月25日; 42(5):413-7。 PMID: 29105469“ Zhang,Shi-Qin Liu,Ye-Ye Tian,Hao Tian,Ling-ling yu
文章隶属关系:cheng-cheng lei
摘要:
目标: diarrhea-predominant irritable bowel syndrome(D-IBS)rats.
METHODS: Fifty SD rats were randomly divided into control, model, EA sensitized acupoint and EA non-sensitized acupoint groups, with 20 rats in the model group and 10 rats在其他三个组中。 D-IBS模型是通过慢性约束应力和胃内胃内吞噬(0.3 g/ml,10 mL/kg)的每天一次建立的,每天一次持续2周,然后进行两周的约束应力刺激。通过在尾部注射后定位Evans Blue(EB)染料的外外点,并用EA(2 MA,2 Hz)刺激30分钟,每天连续7天,确定了敏化的穴位。对于EA非敏化穴位组的大鼠,双侧BL 15被相同的参数和相同的刺激持续时间刺激。通过Bristol凳子量表(BSS),松散的粪便和腹泻指数评估大鼠肠迁移率。
结果: 在建模后,BSS,宽松的粪便率和diarrhea索引分组(plosection)组成了0次模型(persect)。治疗后,BSS,第7天的BSS,松散的粪便和腹泻指数为C在EA-BL 25组中略有降低(p <0.05),但在EA-BL15组中却没有降低(p <0.05),这表明EA对敏化的兆头具有更好的治疗作用。 No significant changes were found in the abovementioned 3 indexes on day 4 after the treatment relevant to the model group (P<0.05).
CONCLUSIONS: EA stimulation of the sensitized acupoint can improve diarrhea in D-IBS rats.