Click here to read the complete article.
Abstract Title:Anti-inflammatory Effect of a Combination of Cannabidiol andExtract on脂多糖刺激的RAW264巨噬细胞。
摘要来源：
体内。 2023; 37（2）：591-595。 PMID： 36881078
atractive futior（s） Natsumi Tomida，Akemi Uwaya，Fumiyuki Isami，Takami Yokogawa，Yutaka inoue 文章隶属关系：takashi tanikawa
摘要：
许多与炎症有关的疾病。大麻sativa和Morinda Citrifolia长期以来一直在民间医学中用于治疗炎症。大麻二醇是最丰富的非PSC. sativa中的YCHO活性植物大麻素，并表现出抗炎活性。 The objective of this study was to examine the anti-inflammatory effect of cannabidiol in combination with M. citrifolia and compare its effects with those of cannabidiol alone.
MATERIALS AND METHODS: RAW264 cells stimulated with lipopolysaccharide (200 ng/ml) were treated with cannabidiol （0-10μm），米拉柑橘种子提取物（0-100μg/ml），或同时组合8或24 h。 Following the treatments, nitric oxide production in the activated RAW264 cells and the expression of inducible nitric oxide synthase were assessed.
RESULTS: Our results showed that combination of cannabidiol (2.5μM) and M. citrifolia seed extract (100μg/ml) exhibited more efficient inhibition of一氧化氮的产生比单独的大麻二醇治疗在脂多糖刺激的RAW264细胞中。组合治疗还降低了诱导型一氧化氧化物合酶的表达。
结论： 这些结果表明，与大麻二醇和瓜米氏菌群提取物相结合的治疗的抗炎作用会导致collistiatormator