摘要标题:
反式效果的cit citral and raction and cription and privation and Impact and Impact and Impact and Impact and Impact and Impact p> p/presptim p> p/presptim p> prymiss p> p/prespt。
炎症。 2017年10月; 40(5):1735-1741。 PMID: 28667503“> 28667503
abforts crip temcon temcon temcon temicon temisis temisis clilia cluria a,cll lia clarlia a,cluria a,clulia clar a mota,mot a mot,mot,MOT Hiruma-lima,Joséantunes-Rodrigues,EvelinCárnio,Luiz g s branco 文章隶属关系:maycontemílio-silva
摘要:citral citral是两个单型动物(neral and saftery as Artial as a andery as a nertary as a neral as a andery)的混合物(由美国食品和药物管理局)。体外研究报告了柠檬质减少炎症的能力。在这里,我们使用最受欢迎的mod报告了citral在体内的抗热力作用EL疾病综合征,即将脂多糖(LPS)全身施用给大鼠。 Citral given by gavage caused no change in control euthermic rats (treated with saline) but blunted most of the assessed parameters related to the sickness syndrome [fever (hallmark of infection), plasma cytokines (IL-1β, IL-6, and TNF-α) release, and prostaglandin E(PGE) synthesis (both peripherally and hypothalamic)].此外,LPS导致血浆皮质酮水平急剧增加,而citral并未改变。这些数据与Citral具有非依赖皮质酮的有效抗药物作用的观念一致,该效应作用于外围额外信号传导(IL-1β的血浆水平,IL-6,TNF-6,TNF-α和PGE),最终使下调下丘脑PGEPGERODUCTION。