这些发现证实，胸醌有可能用于打击单核细胞增生的感染

Xin Miao

This study aimed to determine the antimicrobial activity of thymoquinone (TQ) against, and to examine its inhibitory effects on biofilm formation, motility, hemolysin production, and attachment-invasion of host cells. TQ的最小抑制浓度（MIC）针对八种不同的抑制浓度范围为6.25-12.50μg/ml。水晶紫罗兰色G表明，TQ以剂量依赖性的方式清楚地降低了子摄氏的生物膜生物量。扫描电子显微镜表明TQ抑制了载玻片上的生物膜形成，并诱导了生物膜结构的明显崩溃。 At sub-MICs, TQ effectively inhibited the motility ofATCC 19115, and significantly impacted adhesion to and invasion of human colon adenocarcinoma cells as well as the secretion of listeriolysin O. Supporting these findings, real-time quantitative polymerase chain reaction analysis revealed that TQ down-regulated the transcription of genes associated with motility, biofilm formation, hemolysin secretion, and attachment-invasion在宿主细胞中。总体而言，这些发现证实了TQ有可能用于对抗。