蜂胶在蛋白尿，水晶尿，肾毒性和肝毒性中诱导的乙二醇摄入。
摘要来源：
Arch Med Res。 2016年10月； 47（7）：526-534。 PMID： 28262194 Al-Waili，Badiaa lyoussi
文章隶属关系：nawal el Menyiy
摘要：
背景和目标： propolis propolis是具有广泛的生物学活动和潜在的治疗性的天然蜂蜜产品。该研究的目的是评估丙二醇提取物对大鼠乙二醇诱导的肾毒性和肝毒性的保护作用。第1组接受饮用水，第2组接受了0.75％的乙烯 - 饮料乙二醇ing water, group 3 received 0.75% ethylene-glycol in drinking water along with cystone 500 mg/kg/body weight (bw) daily, group 4 received 0.75% ethylene-glycol in drinking water along with propolis extract at a dose of 100 mg/kg/bw daily, and group 5 received 0.75% ethylene-glycol in drinking water along with propolis extract at a dose of 250 mg/kg/bw 日常的。治疗持续了30 d。 Urinalyses for pH, crystals, protein, creatinine, uric acid and electrolytes, and renal and liver function tests were performed.
RESULTS: Ethylene-glycol increased urinary pH, urinary volume, and urinary calcium, phosphorus, uric acid and protein excretion.它降低了肌酐清除率和镁并引起晶体尿。用蜂胶提取物或塞通岩处理将镁，肌酐，钠，钾和氯化物的水平归一化。蜂胶比雪花石更有效。蜂胶提取物减轻尿蛋白Excretion and ameliorates the deterioration of liver and kidney function caused by ethylene glycol.
CONCLUSIONS: Propolis extract has a potential protective effect against ethylene glycol induced hepatotoxicity and nephrotoxicity and has a potential to treat and prevent urinary calculus,晶状体和蛋白尿。