res Pharm Sci。 2021 Jun; 16（3）：294-304。 EPUB 2021 5月12日。PMID： 342221063“> 34221063 Shirpoor，Masoumeh Pourjabali，Leila Chodari
文章隶属关系：minoo shirpoor
摘要：
背景和目的： 涉及特定的分子中间体，而不是与孕妇相关的特定分子中间人。因此，当前的研究是试图研究中度有氧运动和姜黄素给药的尝试是否减轻异常ities caused by aging in the rats liver.
Experimental approach: Thirty-two eight-year-old young rats were classified into five groups, namely, young control, aged control, aged-curcumin, aged-exercise, and aged-curcumin-exercise co-treatment. The rats in the exercise groups were trained on an animal treadmill for 60 min/day five times per week for eight weeks.
Findings/Results: The results revealed a significant increase in FAT/CD36, PTP1B, significantly decreased HNF4α genes expression, increase in LDL and cholesterol in the aged group compared到年轻的控制。与年轻对照组相比，在老年对照中未观察到HDL和TG量的显着变化。此外，与年轻对照相比，老年组显示肝组织学变化，例如纤维化和轻度或1级脂肪性肝炎。适度的有氧运动和姜黄素单独或组合完全掩盖了这种效果。
结论和含义：