摘要来源: acta ophthalmol。 2017年6月; 95(4):E270-E277。 EPUB 2016 12月18日。PMID: 27989012“> 27989012 G Walker, Robert G Devenyi Graham F Merry PURPOSE: To evaluate the efficacy of photobiomodulation (PBM) treatment for patients with dry age-related macular degeneration (AMD). 方法: 42眼中的评估干燥AMD(年龄相关眼科研究(AREDS)2-4)进行了。多波长的发光二极管(LED)的光包括黄色(590 nm),红色(670 nm)和近红外(790 nm)带宽,以进行受试者的眼睛,以进行3周的治疗过程。 Outcome measures were changes in best-corrected visual acuity (BCVA), contrast sensitivity (CS), drusen volume and central drusen thickness. RESULTS: Significant improvement in mean BCVA of 5.90 letters (p < 0.001) was seen on completion of the 3-week treatment and 5.14 letters (p <0.001)3个月后。 Contrast sensitivity improved significantly (log unit improvement of 0.11 (p = 0.02) at 3 weeks and 3 months (log unit improvement of 0.16 (p = 0.02) at three cycles per degree. Drusen volume decreased by 0.024 mm(p < 0.001) and central drusen thickness was significantly reduced by a mean of 3.78 μm (p < 0.001), while overall central retinal thickness and retinal volume remained稳定。 结论: 这是第一项研究,证明了通过PBM疗法在干燥AMD受试者中的功能和解剖结局的改善。这些发现证实了一项早期的试验研究,研究了功能性结果测量方法。解剖学证据的增加有助于进一步开发非INVAS PBM PBM/PBM