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Abstract Title:Saffron (), Combined with Endurance Exercise, Synergistically Enhances BDNF, Wistar大鼠中的5-> restonin和NT-3。 2021年1月； 9（4）：426-434。 PMID： 33969136“> 33969136 Soudabehsadat Mortazavian，Amir-Hossein Memari，Farzad Shidfar，Ali Shahbazi，Javad Heshmati
文章隶属关系：Maryam Akbari akbari-fakhrabadi
基于运动和营养有益于神经发育。我们旨在确定藏红花和耐力训练对海马神经源性因子，神经营养蛋白3基因表达的影响Leus肌肉和Wistar大鼠中的短期记忆。方法： 该研究分析了四组10只大鼠：对照，运动，锻炼，saffron和saffron和Saffron和Saffron Plus练习。运动组中的大鼠接受了啮齿动物运动驱动的跑步机的训练。所有大鼠每天都用藏红花提取物（40 mg/kg）或水烤。干预八周后，使用新颖的对象识别（NOR）测试对所有大鼠进行了评估。 Blood and tissue samples were collected to measure proteins and neurotrophin-3 gene expression.
Results: Rats that received saffron treatment combined with exercise had significantly greater brain-derived neurotrophic factor () and serotonin in hippocampus compared to the control and saffron-only-treated大鼠（p <0.05）。在藏红花和运动组中，比目鱼肌肉中的神经营养蛋白3 mRNA高于其他三组的大鼠（p <0.05）。河马ampus 5-hydroxyindolacetic acid and short-term memory were significantly greater in all the intervention groups than in the control group (p<0.05).
Conclusion: Saffron, combined with endurance exercise, synergistically increased hippocampus BDNF, serotonin, and muscular Wistar大鼠中的神经营养蛋白3 mRNA。