鲁丁蛋白通过靶向水通道蛋白1水平,大鼠氧化应激,凋亡和炎症来保护氯化汞诱导的肾毒性。
抽象来源:
j trace trace trace Elem Med Biol。 2019年7月; 54:69-78。 EPUB 2019年4月18日。PMID: 31109623“> 31109623 Yildirim,Sefa Kucukler,Gizem Eser
文章隶属关系:Cuneyt caglayan
摘要:
目标: 水星是一种危险的工业和环境危害者,在动物中造成了危险的工业和环境危害,在多样的organs中造成了严重的损害。 The aim of this study was to investigate the protective effect of rutin (50 and 100 mg/kg body weight) against mercuric chloride (HgCl) (1.23 mg/kg b.w.) toxicity in rats.
METHODS: The experiment was carried out in maleSprague Dawley大鼠(n = 35)分为五组,如下:对照,Rutin-100,HGCL,HGCL+ Rutin-50和HGCL+ Rutin-100。
CONCLUSION: The present study indicated that rutin has a nephroprotective effect due to its anti-inflammatory,抗氧化剂和抗凋亡特性。