鲁丁蛋白可以改善氧化应激，并保留暴露于镉和乙醇后的肝功能和肾功能。
摘要来源：
pharm Briol。 2017年12月; 55（1）：2161-2169。 PMID： 29025321“> 29025321 劳伦斯（Lawrence），iniobong a查尔斯（Charles），犹太人c ikewuchi
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MATERIALS AND METHODS: Wistar rats were treated with Cd （50 mg/kg）单独或在联合中用EtOH（5 mg/kg）和车辙（25、50和100 mg/kg）持续15天。 After treatment, the liver, kidney and serum were removed for biochemical assays by spectrophotometric methods.
RESULTS: Serum, hepatic and renal malondialdehyde (MDA) levels were highest in the Cd + EtOH group and lowest in Cd + EtOH animals co-treated with the highest rut剂量（2.98±0.34，10.08±2.32，4.99±1.21 vs. 1.69±0.33，6.13±0.28，3.66±1.12μmolMDA/mg蛋白）。与与100 mg/kg ruT共同治疗的CD+ETOH动物相比，CD+ETOH处理的动物的CD水平升高（2.54±0.08 vs. 1.28±0.04 ppm）。此外，在最高剂量的情况下，胆红素和尿酸水平的升高以及乳酸脱氢酶和γ-谷酰基转移酶的活性（62.86±2.74 vs. 122.52±6.35 µmol/l; 1.77μmol/1.77±0.35 vs. 3.23555555）; 9.56±1.22 vs. 16.21±1.64 U/L； ±40.12 vs. 159.8±18.01 u/l）。 The histo-pathological changes in the liver and kidney were also reduced inthe Cd + EtOH animals co-treated with RUT in a dose-dependent manner.
DISCUSSION AND CONCLUSION: RUT protected against the combined effects of Cd + EtOH on hepatic and renal functions and improved the antioxidant defence system in the血液。