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Abstract Title:Serum magnesium is inversely associated with coronary artery calcification in the Genetics of Atherosclerotic Disease (GEA)研究。
摘要来源:
Nutr J. 2016; 15(1):22。 EPUB 2016 3月1日PMID: 26931571 26931571 Posadas-Romero,Guillermo Cardoso-Saldaña,Gilberto Vargas-Alarcón,MaríaTeresaVillarreal-Molina,NonanzitPérez-Hernández,JoséManuelRodríguez-Pérez,Aida Medina-Medina-Medina-urrutia,Esteban-rroutia,Esteban-Galz-juan juangararza Torres-Tamayo
文章隶属关系:Rosalinda posadas-sánchez
摘要:
背景: 血清镁与冠状动脉钙化(CAC)中的镁(CAC)在患有慢性肾脏疾病的患者。在普通健康人群中,几乎没有有关这种关联的信息。
目标: 这项研究的目的是检查血清镁水平与CAC的横截面关联与Cac。 0的横截面关联。 (LDL-C)和high density lipoprotein cholesterol (HDL-C), triglycerides, diuretic use, type 2 diabetes mellitus (DM2), and family history of DM2.RESULTS: After full adjustment, subjects in the highest quartile of serum magnesium had 48 % lower odds of高血压(P = 0.028),DM2的几率(P = 0.003)低69%,CAC得分的几率> 0(P = 0.016)低42%(p = 0.016)。 The analyses also showed that a 0.17 mg/dL (1SD) increment in serum magnesium was independently associated with 16 % lower CAC (OR 0.84, 95 % CI 0.724-0.986).
CONCLUSIONS: In a sample of Mexican-mestizo subjects, low serum镁不仅与高血压和DM2的较高患病率有关,而且与冠状动脉钙化相关,这是动脉粥样硬化的标志,是心血管发病率和死亡率的预测因素。