妊娠期间的母体硒缺乏症与中国人口中LBW和SGA新生儿的风险呈正相关。
摘要来源:
eur J Clin Nutr。 2021年2月18日。EPUB 2021 2月18日。PMID: 33603150“> 33603150 Feng,Jun Li,Jia-Hu Hao,Peng Zu,De-Xiang Xu,Fang-Biao Tao,Hua Wang
文章隶属关系:Xiang Zhang
摘要:
However, it remains controversial whether maternal Se deficiency during gestation enhances the risks for low-birth-weight (LBW) and small-for-gestational-age (SGA) newborns.
METHODS: For our cohort study, total 3133 mother-and-infant pairs were selected.孕妇血清SE浓缩通过石墨炉原子吸收光谱法检测到三。 According to international references for maternal serum Se concentration, subjects were divided into Se deficiency (<45.0 μg/L), Se insufficiency (45.0-94.9 μg/L) and Se sufficiency (≥95.0 μg/L).
RESULTS: There was a positive relation of maternal serum Se妊娠和新生儿出生体重的浓度。 Further analysis showed that the risks for LBW and SGA in SD group were significantly higher than that in SI and SS group, the adjusted ORs for LBW and SGA newborns were 1.87 (95%CI: 1.02, 3.45; P = 0.04) and 1.47 (95%CI: 1.07, 2.02; P = 0.02) in SI group, and 3.92 (95%CI: 2.03, 7.57; p <0.001)和2.77(95%CI:1.92,4.02; p <0.001)与SS组相比。在不同的性别亚组中,孕产妇SE缺乏症与LBW女孩的风险之间观察到了积极关系,以及SGA女孩和男孩的风险。
结论:妊娠中的孕产妇SE缺乏症与LBW女孩的风险正相关,以及SGA女孩和男孩的风险。