抵抗训练可以影响MRI结果在复发的多发性硬化症中吗?
摘要来源:
多scler。 2017年7月1日:1352458517722645。 EPUB 2017年7月1日。PMID: 28752800 28752800 Wenzel,Jan-Patrick Stellmann,Steffen Ringgaard,Bodil Ginnerup Pedersen,Egon Stenager,Egon Stenager,Thor Petersen,Kristian Vissing,Christoph Heesen,Christoph Heesen,Ulrik Dalgas
文章隶属关系:多发性硬化症(MS)的特征是加速脑萎缩,这与疾病进展有关。先前的研究表明,进行性抗性训练(PRT)可以抵消其他人群中的脑萎缩。
目标: 通过磁共振成像评估PRT的效果(MR)I) and clinical measures of disease progression in people with MS.
METHODS: This study was a 24-week randomised controlled cross-over trial, including a Training ( n = 18, 24 weeks of PRT followed by self-guided physical activity) and Waitlist group ( n = 17, 24 weeks of habitual lifestyle followed by PRT). Assessments included disability measures and MRI (lesion load, global brain volume, percentage brain volume change (PBVC) and cortical thickness).
RESULTS: While the MS Functional Composite score improved, Expanded Disability Status Scale, lesion load and global brain volumes did not differ between groups. PBVC在组之间趋于不同,并且在PRT后74个研究的皮质区域中有19个观察到了较高的绝对皮质厚度值。比较组之间的相对皮质厚度变化时,确认并复制了观察到的变化。r四个区域:前扣带回,颞极,眶沟和下颞沟。
结论: prt prt似乎诱导了prt的厚度,表明prt具有神经性效应,甚至是神经性效应的效果MS。