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Abstract Title:Effect of the Ginger Derivative, 6-Shogaol, on Ferritin Levels in Patients With Low to中级1风险骨髓增生综合征 - 一项小型调查研究。
摘要来源:
clin Med Med Insights血液疾病。 2017; 10:1179545x17738755。 EPUB 2017 11月2日。PMID: 29147080 Manoharan, Rajeev Ramakrishna, Vladimir Badmaev
Article Affiliation:Terry Golombick
Abstract:Background: Myelodysplastic syndrome (MDS) is a heterogeneous group of clonal stem cell disorders characterized by dysplastic and无效的造血和周围细胞质。经常观察到升高的血清铁蛋白(SF)在非转让,较低的风险MD中进行了ed。 It has been reported that ineffective erythropoiesis enhances iron absorption in MDS through downregulation of hepcidin and its prohormones such that SF rises.
Aim: To determine the effect of 6-shogaol, a dehydration derivative of ginger, known to have hepatoprotective and chemotherapeutic activity, on 6 early-stage, transfusion-independent patients with MDS, 3 of whom had raised levels of SF.
Method: Six patients with MDS with low or intermediate-1 subtypes, as defined by the International Prognostic Scoring System (IPSS), were recruited into the study and were每天施用1个凝胶胶囊,其中含有20毫克姜提取物,标准化为20%6-肖尔。收集血液和尿液样品,并定期监测各种标记。
结果: 6-shogaol引起了D在研究开始时,在6例早期MDS(50%)患者中有3例SF水平的Ecrease在研究开始时升高。我们的发现表明,肝素及其激素的上调可能是通过改善肝功能。
讨论: 鉴于这项小型研究中的较大的研究,我们正在为6-shog的效应而促进较大的研究,从而在较大的研究中获得较大的研究,从而在6-shog的效果中获得6-shog的效果,以实现6-shog的效果。 erythropoiesis。