生物氨酸A对异丙肾上腺素诱导的大鼠心肌梗死的治疗潜力。
摘要来源：
心哥省尾醇药物药物。 2020年2月5日。epub 2020 Feb5。pmid： 32026788 32026788 Veera Venkata Sathibabu Uddandrao, Nivedha Raveendran, Vadivukkarasi Sasikumar
Article Affiliation:Sangeethadevi Govindasami
Abstract:BACKGROUND: This study determined the effect of Biochanin A (BCA) on isoproterenol (ISO) induced myocardial infarction (MI) in male Wistar rats.
METHODS: Animals (Weighing 150-180 g) were divided into four groups, with six animals in each group and pretreated with BCA (10mg/kg body weight [BW]和托酚（60mg/kg bw 30天； ISO（20mg/kg bw）被管理在第31和32天的皮下额定评级。
结果： ISO诱导的MI大鼠，表明血清血清谷氨酸乙酰乙酸草乙酸乙酰乙酰乙酰氨基糖化酶，血清谷氨酸型糖酶形成型和丙氨酸酶，裂解酶，裂缝酶，裂缝，裂解酶，裂解酶，裂解酶，裂开肌钙蛋白；然而，与BCA的伴随预处理保护了大鼠免受ISO引起的心脏毒性。抗氧化酶的活性，例如超氧化物歧化酶，过氧化酶，谷胱甘肽过氧化物酶，谷胱甘肽-S-转移酶和谷胱甘肽还原酶的活性在心脏中使用ISO诱导的MI显着降低。 Pretreatment with BCA produced a marked reversal of these antioxidant enzymes related to MI¬¬-induced by ISO.
CONCLUSION: In conclusion, this study suggested that BCA exerts cardioprotective effects through modulating lipid peroxidation, enhancing antioxidants, and排毒酶系统。