芝麻对Wistar大鼠中异丙醇引起的心肌梗死的保护作用。
摘要来源:
redoxRep。2010; 15(1):36-42。 pmid: 20196927 Pugalendi
文章隶属关系:
印度泰米尔纳德邦Annamalainagar 608 002的科学学院生物化学和生物技术系Wistar老鼠。 The heart damage induced by ISO was indicated by elevated levels of the marker enzymes such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), creatine kinase (CK), creatine kinase-MB (CK-MB) and the levels of troponin T and I in the plasma.在Additio中N,脂质过氧化标记物(例如硫巴比妥酸反应性物质(TBAR),共轭二enes(CD)和脂质氢过氧化物(LHP)(LHP)在等离子体和心脏中显着增加。 Activities of superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione-S-transferase (GST) and glutathione reductase (GR) significantly decreased in the heart and (non-enzymic antioxidants) vitamin C, vitamin E and reduced glutathione (GSH)) levels significantly decreased in the plasma and heart in ISO大鼠。组织病理学观察与生化参数相关。以不同剂量的50、100和200 mg/kg的体重腹膜内服用芝麻醇7天,可以阻止上述变化,并改善了正态性。 50 mg剂量比其他两剂更有效。