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Abstract Title:The Effect of Repeated Low-Level Red-Light Therapy on Myopia Control and Choroid.
Abstract Source:
转换Vis Sci技术。 2024年10月1日; 13(10):29。 PMID: 39432402”> 39432402 Yan Xiang
文章隶属关系:ying liu
摘要:
目的: 研究重复的低级红光(rlrl)对轴向长度(Al),spherical equilital equialtal(se)的长期影响(rlrl)治疗的长期影响参数。
方法: 招募了两百八个近视眼。 RLRL组包括100眼,而对照组包括108眼。在整个一美R随访期,两组的AL和SE的变化均已记录。 The RLRL group underwent additional choroidal imaging, and changes in choroidal thickness (CT), choroidal vascularity (CV), and choriocapillaris luminal area (CLA) were assessed before and after RLRL therapy.
RESULTS: During the follow-up period, the changing RLRL和对照组之间AL和SE的趋势差异很大。在RLRL组中,AL在三个月和六个月(均为p <0.05)下降,并在12个月时返回预处理值(p = 0.453)。相比之下,在对照组的整个随访期(三个,六个月和12个月)中,AL显着增加(所有p <0.001)。在RLRL组的整个随访期间,SE显着增加(所有p <0.001),而对照组中的SE显着下降(所有p <0.05)。关于脉络膜参数,在CT,CV和CLA THR中观察到显着改善Oughout随访期(所有p <0.05),大多数脉络膜参数的变化与随访期间的AL和SE的变化显着相关(所有P <0.05)。 Furthermore, AL, SE, and most choroidal parameters showed significant correlations between changes at three and 12 months (all P<0.05).
CONCLUSIONS: RLRL therapy significantly improved choroidal blood perfusion and circulation, which may explain the observed slowing or reversal of myopia progression in the RLRL组。因此,RLRL治疗可能是控制近视的一种新颖有效的方法。 Furthermore, the short-term effect of photobiomodulation therapy (i.e., changes at three months) can be used to predict the long-term effects (i.e., changes at 12 months).
TRANSLATIONAL RELEVANCE: In this study, RLRL therapy showed a significant control effect on the development of axial length and sp同等的。 RLRL治疗还促进了脉络膜血液灌注和循环。 RLRL治疗可能是近视控制的一种新颖有效的方法。