对儿童近视的控制重复的低级红光治疗：随机对照试验的荟萃分析。
摘要来源：
眼神触角。 2023年10月1日; 49（10）：438-446。 EPUB 2023 8月8日。PMID： 37565498> 37565498 Jiang
文章隶属关系：fei wang
摘要：
背景： 重复的低级红光（RLRL）疗法已被建议在儿童中有效。但是，来自随机对照试验（RCT）的证据仍然有限。 We performed a meta-analysis of RCTs to systematically evaluate the efficacy of RLRL on changes of axial length (AL) and cycloplegic spherical equivalent refraction (SER) in children with myopia.
METHODS: Relevant RCTs were obtained through从成立到2022年9月15日，搜索包括PubMed，Embase，Cochrane图书馆，Wanfang和中国国家知识基础设施在内的电子数据库的搜索。在结合潜在异质性的影响后，使用随机效应模型来填充结果。根据对照处理和随访持续时间进行亚组分析。
结果： 总共涉及1,031名与近视的儿童，年龄在6至16岁之间，年龄在6至16岁之间，包括6至16岁的儿童。 Compared with control treatment without RLRL, treatment with RLRL was associated with a significantly reduced AL (mean difference [MD]: -0.25 mm, 95% confidence interval [CI]: -0.32 to -0.17, P<0.001; I 2 =13%) and a significantly increased cycloplegic SER (MD: 0.60 D, 95% CI: 0.44-0.76, P<0.001; I 2 = 20％）。进一步的亚组分析表明，在比较穿着单视镜的儿童的研究中，结果一致ctive treatment including orthokeratology or low-dose atropine eye drops, as well as studies of treatment duration of 6 and 12 months.
CONCLUSIONS: Results of the meta-analysis suggested that RLRL treatment is effective for slowing down the progression of myopia in children aged 6 to 16年。