乳铁蛋白和坏死性小肠结肠炎

评论目的： 新生儿护理人员在肠乳脂素中对肠内的肠胃外丝素在肠内的兴趣是否会减少在预科属于预科属性的肠结构炎的发生率。 This review presents scientific and clinical evidence that lactoferrin alleviates or prevents this life-threatening disease.

RECENT FINDINGS: Preclinical studies in neonatal rats showed that lactoferrin given orally before enteral infection with pathogenic Escherichia coli reduced bacteremia and mortality.一项多中心临床试验发现，牛乳铁蛋白的非常低的体重早产儿的晚期败血症显着降低。还存在坏死性小肠结肠炎发病率降低的趋势。 Although multicentered trials of lactoferrin use in preterm infants are near completion, regulatory burdens required to bring lactoferrin to the bedside may limit its availability.

SUMMARY: Extremely preterm infants should receive colostrum, a natural lactoferrin concentrate, immediately after birth and, ideally, continue on breast整个医院的牛奶住宿。这种做法似乎很容易容忍，但是额外的经验会告诉我们这种做法是否降低了坏死性小肠结肠炎的患病率。