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Abstract Title:Berberine enhances L1 expression and axonal remyelination in rats after brachial plexus root撕裂。
抽象来源：
脑行为。 2020年8月7日：E01792。 EPUB 2020 8月7日。PMID： 32770668“> 32770668 Zhou，Yan Xu，Lin Wu，Yangzhi Xie，Yihui Li，Shuangqin Chen，Jianghua Huang，Heng Wu，Heng Wu，Zijian Xiao
文章隶属关系：shuangxi chen
shuangxi chen 摘要：p>
METHODS: The surgical procedures were performed to build the rat brachial plexus avulsion and re-implantation model, and then, the rats were treated with BBR。 After the rehabilitation for 12 weeks, the musculocutaneous nerves were collected for quantitative real-time PCR, Western blot analysis, and histochemical and immunofluorescence staining.
RESULTS: We observed that, BBR treatment ameliorated the abnormal musculocutaneous nerve fibers形态上调L1表达，增加了与髓鞘相关的基因，降低了与分化相关的基因，并上调了ERK的磷酸化。<<<<<<
结论： 这些结果表明，BBR可以增强L1表达并促进脊髓根侵蚀后的轴突再髓。